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The Hallmarks of Aging | LifeXtenShow

Let's face it: you're getting old, but there's a reason—or, rather, there's nine. This episode is all about the hallmarks of aging, the microscopic conspirators inside your body that are plotting to slowly take away your health. Liked the show? Let us know on Twitter at   / lifespanio   or our Discord server at   / discord   Facebook:   / lifespanio   LinkedIn:   / lifespanio   Instagram:   / lifespan.io   Website: https://www.leafscience.org/ Stock contents: Shutterstock, Videoblocks Music: Intro jingle courtesy of Kevin MacLeod - Incompetech.com -------------------------- Sources: The Hallmarks of Aging: López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2013). The hallmarks of aging. Cell, 153(6), 1194-1217. (Available for free here: https://www.cell.com/abstract/S0092-8...) Oncogenes can be flipped on epigenetically: https://www.ncbi.nlm.nih.gov/pmc/arti... Senescent cells and wound healing: https://www.sciencedaily.com/releases... Insulin resistance in human aging: Chen, M., Bergman, R. N., Pacini, G., & Porte Jr, D. (1985). Pathogenesis of age-related glucose intolerance in man: insulin resistance and decreased β-cell function. The Journal of Clinical Endocrinology & Metabolism, 60(1), 13-20. -------------------------- #Aging #Biology #HallmarksOfAging #Science #LifeExtension #Telomeres #Mitochondria #Epigenetics #DNADamage #CellularSenescence #NutrientSensing #Inflammation #StemCells #Proteins #Proteostasis ►Subscribe for more: http://www.youtube.com/user/LifespanI... ►This video is presented by LEAF. Please support our work by becoming a Lifespan Hero: http://lifespan.io/hero