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NCCN Patient Webinar: Multiple Myeloma

Experts discussed what to expect from CAR T-cell therapy for multiple myeloma, autologous stem cell transplant, managing the costs of cancer care, and more. Topics Discussed 00:00 Welcome and Introductions 02:23 Outline of what to expect during CAR T-cell therapy 03:15 Definitions of T-cell and CAR T-cell 05:51 Who is eligible for CAR T-cell therapy 06:39 What are CAR T-cell options? 09:29 After you decide on CAR T-cell therapy 09:58 Brain to vein time and who needs treatment during this period 12:58 Vein to vein time 15:48 CAR T-cell infusion 16:27 After CAR T-cell infusion and side effects 19:05 Immune recovery and follow-up schedule 20:08 Pre-stem cell transplant evaluation 21:42 Getting ready for transplant 23:16 Your transplant team 23:31 Caregiver roles 24:58 IV catheter 25:21 Apheresis aka stem cell collection 26:36 Chemotherapy - melphalan 27:24 While you're in the hospital 29:49 Care needs immediately after transplant and returning home 32:22 Day 100 after transplant 33:36 Experiences from a multiple myeloma patient advocate 35:26 What is financial toxicity and contributing factors? 36:47 Impact of contributing factors 38:22 Cancer statistics 38:58 What steps do you take as a newly diagnosed patient? 41:13 Summary and resources Q&A Session 42:20 When CAR T-cell therapy becomes more widely available, will costs decrease? 45:18 Can you discuss first-line chemotherapy for multiple myeloma? 48:06 Would high-risk and extramedullary multiple myeloma be a good fit for CAR T? 49:04 What is the risk of giving a bone marrow transplant to a patient with a history of heart surgery? Is bone marrow transplant the same as stem cell transplant? 50:22 Is it possible to enroll someone who is not a US citizen for CAR T or stem cell with a financial waiver? 52:16 What are the current recommendations for CAR T? Do you need to have a previous transplant? How do the pros and cons compare to stem cell transplant? 55:36 I am currently doing water aerobics- is this an acceptable exercise after I return from stem cell? 57:33 When someone gets an organ transplant, there is danger that it will be rejected by the body. Is there a rejection possibility with stem cell transplant? 58:45 Some hospitals have programs for coverage of financial debt after Medicare and insurance coverage. Are there similar programs available to assist patients country-wide? 1:00:28 If have homeowner's insurance and a tree falls on your house, instead of dealing with the insurance company directly you can call a public claims adjuster to work on your behalf. Is there anything like that with health insurance? Are there ways to better understand costs? 1:05:03 If your doctor recommends CAR T, where do you go to get it? 1:06:22 Does lenalidomide (revlimid) contribute to peripheral neuropathy? 1:07:07 Can you do a stem cell transplant after CAR T? 1:07:21 What is T-cell exhaustion? 1:08:27 Are consecutive anti BCMA treatments possible before CAR T? 1:09:17 Do pharmaceutical companies have financial assistance programs? The Patient Webinar on Multiple Myeloma occurred in October 2023. This program was created in conjunction with the NCCN Guidelines for Patients® for Multiple Myeloma: https://www.nccn.org/patientresources... The NCCN Guidelines for Patients are available to read and download for free online and via the NCCN Patient Guides for Cancer mobile app. Printed editions can be ordered from Amazon.com for a small fee. NCCN Guidelines for Patients DO NOT replace the expertise and clinical judgment of the clinician. Supporters: This webinar is supported through the NCCN Foundation and by contributions from our corporate supporters: Bristol Myers Squibb and Janssen Biotech, Inc. __________________________________________________________ About NCCN Foundation®: NCCN FOUNDATION® is a 501(c)3 organization founded by the National Comprehensive Cancer Network® (NCCN®)—a not-for-profit alliance of leading cancer centers devoted to patient care, research, and education—to empower people living with cancer and advance oncology innovation. For more information or to make a donation, visit http://www.nccn.org/patients/foundation __________________________________________________________ About NCCN: The National Comprehensive Cancer Network® (NCCN®) is a not-for-profit alliance of leading cancer centers devoted to patient care, research, and education. NCCN is dedicated to improving and facilitating quality, effective, equitable, and accessible cancer care so all patients can live better lives. Visit https://www.nccn.org/ for more information. Subscribe to our channel for the latest in cancer care: https://www.youtube.com/c/NCCNvideo?s... Connect with us! Twitter:   / nccn   LinkedIn:   / nccn   Facebook:   / nccnorg   Instagram:   / nccnorg