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NCCN Patient Webinar: Pediatric Acute Lymphoblastic Leukemia

Experts discuss how to understand the diagnosis and treatment of pediatric acute lymphoblastic leukemia, how to engage in shared decision-making with your care team, and side effects, clinical trials, and available patient and caregiver resources. Topics Discussed: 00:00 Welcome and introductions 02:24 Clinical overview of pediatric acute lymphoblastic leukemia (ALL) 04:14 How does ALL happen in bone marrow? 06:04 How do we diagnose ALL? 07:54 Incidence of ALL 08:41 Medications used in ALL therapy 09:37 Improved survival in ALL 10:07 Risk stratification of ALL 11:11 Genetic analysis and genetic subtypes of ALL 12:19 Response to therapy: Minimal residual disease (MRD) 14:31 Adverse effects in ALL therapy and individual chemotherapy modification 17:17 New therapeutic approaches of ALL 22:26: Recent research studies on ALL treatment 24:55 Supportive care 26:02 Side effects 27:29 Low blood counts 29:07 Infections 30:07 Fever and how to take a temperature 31:35 Impact on skin, hair, and mucus membranes 33:30 Nutrition 34:45 Nausea and vomiting 35:47 Pain and "chemo brain" 37:50 Side effects of steroids 39:14 Vincristine side effects 40:13 Asparaginase side effects 42:07 Immunotherapy side effects 44:23 Patient story 51:19 Advocating for your child with cancer: Ask questions, share your concerns, get organized, communicate with your child, take care of yourself, find support Question & Answer Session: 55:33 How can children have their own support group? 57:07 Is there a male predisposition to ALL? 58:12 Can other countries have access to immunotherapy or molecular targeted therapy? 59:56 Do you often get questions from providers around the world? 1:00:48 What can we do during treatment to reduce the risk of long-term side effects like heart disease, secondary cancer, etc.? 1:02:48 Should patients avoid multivitamins or certain types of foods during treatment? 1:04:32 How do we measure progress during treatment or effectiveness of the chemotherapy medications? 1:05:35 Any pearls to offer on the use of serum asparaginase activity testing and when to consider changing therapy? 1:06:46 Can you explain half life? Do the side effects continue because of the drug half life? 1:07:38 When you are taken off a drug due to side effects, such as pancreatitis, what does this mean? 1:09:35 Is there a clinical trial about blinatumomab as first-line treatment? 1:10:38 Conclusion The most recent Patient Webinar: Pediatric Acute Lymphoblastic Leukemia occurred in October 2023. This informational program was created in conjunction with the NCCN Guidelines for Patients®: Pediatric Acute Lymphoblastic Leukemia. https://www.nccn.org/patientresources... The NCCN Guidelines for Patients are available to read and download for free online and via the NCCN Patient Guides for Cancer mobile app. Printed editions can be ordered from Amazon.com for a small fee. NCCN Guidelines for Patients DO NOT replace the expertise and clinical judgement of the clinician. Supporters This webinar is supported through the NCCN Foundation and by contributions from our corporate supporters, Amgen Inc. and Jazz Pharmaceuticals, Inc. __________________________________________________________ About NCCN Foundation®: NCCN FOUNDATION® is a 501(c)3 organization founded by the National Comprehensive Cancer Network® (NCCN®)—a not-for-profit alliance of leading cancer centers devoted to patient care, research, and education—to empower people living with cancer and advance oncology innovation. For more information or to make a donation, visit http://www.nccn.org/patients/foundation __________________________________________________________ About NCCN: The National Comprehensive Cancer Network® (NCCN®) is a not-for-profit alliance of leading cancer centers devoted to patient care, research, and education. NCCN is dedicated to improving and facilitating quality, effective, equitable, and accessible cancer care so all patients can live better lives. Visit https://www.nccn.org/ for more information. Subscribe to our channel for the latest in cancer care: https://www.youtube.com/c/NCCNvideo?s... Connect with us! Twitter:   / nccn   LinkedIn:   / nccn   Facebook:   / nccnorg   Instagram:   / nccnorg