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Research lecture presented by Dr. Qing Yu of the University of Massachusettes Chan Medical School. This lecture was presented on August 2, 2024 at the Chemical Tags for Quantitative Omics Workshop. The workshop was organized by Dr. Lingjun Li and her lab at the University of Wisconsin-Madison, School of Pharmacy. Recorded videos for each lecture in the workshop can be found on this YouTube channel. Websites: https://www.lilabs.org, https://www.ncqbcs.com/ This workshop was sponsored by the National Center for the Quantitative Biology of Complex Systems (NQBCS), founded in 2016 through a grant from the National Institute of General Medical Sciences (GM108538) on the campus of the University of Wisconsin-Madison. Our core mission is the development, application, and dissemination of mass spectrometry technology.