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Why Is DOSY So Different From COSY? | Prof. Gareth Morris | Session 80

During the 80th session of the Global NMR Discussion Meetings held on February 13th, 2024 via Zoom, Prof. Gareth Morris from the University of Manchester, United Kingdom, gave a talk on the topic "Why is DOSY so different from COSY?". The recording serves as a tutorial. Prof. Gareth Morris' research group website and bio: https://nmr.chemistry.manchester.ac.u... Abstract: Peaks in COSY, NOESY, ROESY and HSQC 2D spectra either appear where they should, or not at all. In DOSY spectra, it is all too common to see peaks at incorrect positions in the diffusion domain. This tutorial will explore why this happens, what we can do about it, and how to avoid being misled by DOSY spectra. Content of this video : 00:00 - 12:21 Basics 12:22 - 37:15 How to (mis)interpret DOSY data 37:16 - 48:12 How to (over)interpret DOSY data 48:13 - 50:00 How to stay out of trouble 50:01 - 1:16:50 Questions and answers Current organizers: Adrian Draney (Creighton Uni., Chemistry) Amrit Venkatesh (Florida State University, National High Magnetic Field Laboratory) Asif Equbal (New York Uni., Abu Dhabi) Blake Wilson (Robert Tycko Lab, NIH) Michael Hope (Warwick Uni., Chemistry) Mouzhe Xie (Maurer Lab, Uni. Chicago) Nino Wili (Niels Chr Nielsen Lab, Aarhus Uni.) Nesreen Elathram (Debelouchina Lab, UCSD) Charlotte Bocquelet (HMRLab, CRMN Lyon)