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Restoring muscle weakness | 90 Seconds w/ Lisa Kim 9 месяцев назад


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Restoring muscle weakness | 90 Seconds w/ Lisa Kim

A small molecule previously shown to enhance strength in injured or old laboratory mice does so by restoring lost connections between nerves and muscle fibers, Stanford Medicine researchers have found. The molecule blocks the activity of an aging-associated enzyme, or gerozyme, called 15-PGDH that naturally increases in muscles as they age. The study showed that levels of the gerozyme increase in muscles after nerve damage and that it is prevalent in muscle fibers of people with neuromuscular diseases. The research is the first to show that damaged motor neurons — nerves connecting the spinal cord to muscles — can be induced to regenerate in response to a drug treatment and that lost strength and muscle mass can be at least partially regained. It suggests that, if similar results are seen in humans, the drug may one day be used to prevent muscle loss of muscle strength due to aging or disease or to hasten recovery from injury. Read the full story: http://stan.md/3PQqAug Helen Blau, PhD, is a Professor of Microbiology and Immunology at the Stanford University School of Medicine. She is also Director of the Baxter Laboratory for Stem Cell Biology. Lisa Kim is Senior Manager of Media Relations for Stanford Medicine and Stanford Health Care. Lisa has a deep background in journalism, as she is an Emmy Award-winning journalist who has covered stories on both the national and local levels. #MuscleWeakness #Aging #Research . . . Stanford Medicine advances human health through world-class biomedical research, education and patient care. Bringing together the resources of Stanford University School of Medicine, Stanford Health Care and Lucile Packard Children's Hospital, Stanford Medicine is committed to training future leaders in biomedicine and translating the latest discoveries into new ways to prevent, diagnose and treat disease. The Stanford Medicine YouTube channel is a curated collection of contributions from our School of Medicine departments, divisions, students, and the community. Our diverse content includes coverage of events, presentations, lectures, and associated stories about the people of Stanford Medicine.

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