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00:00 - Intro 00:32 - Objectives 00:58 - Case 05:36 – Basic features of headache clinical history 06:36 – Fundoscopy 08:16 – Anatomy of pain: The headache network. 12:31 – Differential diagnosis of primary headache 14:15 – S.N.O.O.P. mnemonic 16:13 – IHS diagnostic criteria for migraine 17:45 - Migraine aura 18:25 - Cluster 21:19 – Treatments for primary headaches 30:14 – Differential diagnosis of secondary headache 30:43 – Idiopathic intracranial hypertension 32:37 – Tumor headache 37:53 – Cerebral venous thrombosis 39:01 – Cervical arterial dissection 40:41 – Giant cell (temporal) arteritis 43:07 – Trigeminal neuralgia 44:58– Case wrap-up 46:56 - Summary: Treatment algorithm This video is intended for medical students to understand the clinical presentation, differential diagnosis and treatment of primary headaches and the wider differential diagnosis of secondary headaches. Created by: Igor Rybinnik, MD Neurology Clerkship Director Rutgers Robert Wood Johnson Medical School Produced and narrated by: Igor Rybinnik MD Special appreciation to my wife, Jane Shmidt PhD, who is a migraine sufferer, for narrating the patient history. Content review: Pengfei Zhang, MD Headache Neurologist Assistant Professor Rutgers Robert Wood Johnson Medical School Images, video clip and audio adapted from: Vislisel J, Venckus T . EyeRounds.org, University of IOWA, 2014. Li J, et al. Experimental and Therapeutic Medicine, 12, 1119-1124 Netter FH. The Netter Collection of Medical Illustrations. 2nd ed. 2013, Saunders. Goadsby PJ, Besbitt AD. BMJ 2012;344:e2407 Pathophysiology of migraine, Springer Healthcare IME, 2020. Parameswaran A, et al. J Oral Maxillofac Surg 2018-76,1873-81 "Let the Real Estate Games Begin." Selling Sunset, season 2, episode 1. Created by Adam DiVello. Netflix, 2019. “Parzival” by William Rosati Mazzucco S, et al. Neurology 2006; 66:E19. Schievink WI. NEJM 2001;344(12):898 Kandel ER, et al. Principles of Neural Science 5th Edition. McGraw Hill, 2012. Nucleus Medical Media, Inc. Haouimi A, Radiopaedia.org, rID: 72159. T Hines, Mayfield Clinic Disclaimer: Please note that this material was simplified for educational purposes. For patient management, please review your clinical society's guidelines and engage expert consultation where appropriate. Also, the opinions of the presenters do not necessarily reflect those of Rutgers Robert Wood Johnson Medical School, Robert Wood Johnson University Hospital, or Rutgers University as a whole.