Скачать с ютуб Fabrication of a Microfluidic Device for the Compartmentalization of Neuron Soma and Axons в хорошем качестве

Fabrication of a Microfluidic Device for the Compartmentalization of Neuron Soma and Axons

A microfluidic device is a small-scale system that uses channels and chambers to manipulate fluids and particles at the microscale level. In recent years, microfluidic devices have been increasingly used in neuroscience research to study the behavior of neurons and their interactions with other cells. One of the key challenges in studying neurons is the need to separate the soma (cell body) from the axons (long, thin projections that transmit signals to other cells). This is because the soma and axons have different properties and functions, and studying them separately can provide valuable insights into how neurons work. To address this challenge, researchers have developed microfluidic devices that can compartmentalize the soma and axons of neurons. These devices typically consist of a series of channels and chambers that are connected by small openings, or "microgrooves." The microgrooves are designed to be narrow enough to prevent the soma from crossing over into the axon compartment, while still allowing the axons to grow through and make connections with other cells. To use the device, researchers first culture neurons in the soma compartment. As the neurons grow and develop, their axons extend through the microgrooves and into the axon compartment. By controlling the flow of fluids and chemicals in the device, researchers can manipulate the environment around the neurons and study their behavior in real time.