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Antianginal Drugs Pharmacology | Dr Najeeb🩺

#antianginal #antianginaldrugs #pharmacology #drnajeeb #medicines Antianginal Drugs Pharmacology | Dr Najeeb🩺 Like this video? Sign up now on our website at https://www.DrNajeebLectures.com to access 1000+ Exclusive videos on Basic Medical Sciences & Clinical Medicine. These are premium videos (NOT FROM YOUTUBE). All these videos come with English subtitles & download options. Sign up now! Get Lifetime Access for a one-time payment of $59 ONLY! Sign up now on our website at https://members.drnajeeblectures.com/... --------------------------------------------------------------------------------------------------------------------------- Why sign up for premium membership? Here's why! Membership Features for premium website members. 1. More than 1000+ Medical Lectures. 2. Basic Medical Sciences & Clinical Medicine. 3. Mobile-friendly interface with android and iOS apps. 4. English subtitles and new videos every week. 5. Download option for offline video playback. 6. Fanatic customer support and that's 24/7. 7. Fast video playback option to learn faster. 8. Trusted by over 2M+ students in 190 countries. --------------------------------------------------------------------------------------------------------------------------- ▬▬▬▬▬▬▬▬▬▬ Contents of this video ▬▬▬▬▬▬▬▬▬▬ 00:00:00 Introduction, what is Angina? 00:03:52 Types of Angina 00:04:52 Pathophysiology of Classical Angina 00:11:50 Pathophysiology of Prinzmetal Angina 00:15:42 Pathophysiology of unstable Angina 00:24:15 Pharmacological strategies to manage classical angina 00:25:58 Pharmacological strategies to manage Prinzmetal Angina 00:30:28 Pharmacological strategies to manage unstable Angina 00:34:50 Preload and after load, Determinants for the work of the heart 00:44:34 How antianginal drugs should work 00:54:40 Reduce the Preload of heart 00:58:30 Example 01:02:07 Reduce the After load 01:08:02 Reduce the heart rate 01:14:50 Long term management of Angina 01:17:46 Classical management of Angina 01:18:16 A) Nitrates 01:19:27 GTN 01:26:00 Isosorbide Dinitrate 01:27:10 Isosorbide Mononitrate 01:29:00 Why mechanism of nitrates loses its action after sometime? 01:38:36 Monday disease 01:42:36 Physiology of smooth muscle contraction and pharmacological action of Nitrates on them 01:56:24 Recap 02:00:34 Adverse effects of Nitrates and their reasons 02:18:08 B) Beta Blockers 02:26:24 Selective and non-selective Beta Blockers 02:29:00 Role of beta blockers in Angina 02:36:49 Combination on Nitrates and Beta blockers in Angina 02:46:35 Adverse effects of Beta Blockers and their reasons 03:28:50 C) Calcium channel blockers 03:39:23 Role of Calcium channel blockers on heart, Heart block and its types 03:58:44 How Calcium channel blockers alter the mechanical and electrical activity of heart? 04:28:58 Adverse effects of Calcium channel blockers --------------------------------------------------------------------------------------------------------------------------- Antianginal agents are drugs used to provide immediate relief from angina symptoms and prevent angina attacks. Angina is chest pain or discomfort that happens because of reduced blood flow to the heart. Angina results from an imbalance in the oxygen supply/demand ratio. Due to the lower oxygen supply and greater oxygen demand, there is increased pressure on the heart. Constriction of blood vessels and formation of blood clots may be the major reason for disturbing the oxygen supply/demand ratio. Antianginal drugs act by: Increasing blood flow to the heart Increasing oxygen supply to the heart Dilating the blood vessels to reduce the load on the heart Preventing clot formation in the blood vessels Reducing oxygen demand by decreasing heart rate and contraction --------------------------------------------------------------------------------------------------------------------------- Join this channel to get access to perks: Sign up now on our website at https://members.drnajeeblectures.com/...    / @doctornajeeb   Follow us on Facebook :-   / drnajeeb   Follow us on Instagram :-   / drnajeeblectures