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The placebo effect is a long-recognised phenomenon that has played an important part in the history of medicine -- from the healing powers of Stonehenge to administering placebo drugs to modern day patients. But it's not until recently that science has begun to truly understand how the placebo effect really works. Professor Nicholas Humphrey asks why placebos work and reveals their central paradox: If we can effectively cure ourselves by taking placebo medicine, why don't we just heal ourselves straight away? Exploring this paradox from the perspective of evolution, Professor Humphry looks at the associated costs and benefits of pain or illness. How can placebo medications readdress this balance and is a "dose of contrived optimism" just what the doctor ordered? Find out more about Prof Nicholas Humphrey: http://www.humphrey.org.uk 10 Unanswered Science Questions This video is part of a series brought together by the All Times 10s YouTube Channel exploring ten unanswered science questions. To view the greatest minds on YouTube respond, follow the link at the end of the video or click below: • Видео Explore the All Times 10s YouTube Channel: / alltime10s Connect with the Royal Institution The Ri is on Twitter: / ri_science and Facebook: / royalinstitution and Tumblr: / ri-science Our editorial policy: http://www.rigb.org/home/editorial-po... Subscribe for the latest science videos: http://bit.ly/RiNewsletter