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Oisín Biotechnologies, Presented By Matthew Scholz, PhD, CEO 1 год назад


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Oisín Biotechnologies, Presented By Matthew Scholz, PhD, CEO

Myth In Celtic myth, Oisín (sometimes Ossian) was the Gælic warrior-bard of the 7th century who sought the land of youth – a magical island off the western coast of Ireland. Today Oisín Biotechnologies is working to make the myth a reality. Reality Oisín Biotechnologies' ground-breaking research and technology is demonstrating that the solution to mitigating the effects of age-related diseases is to address the damage created by the aging process itself. We invite you to see how. Our First Target - Senescent Cells When cells detect that they have been irreversibly damaged, they enter a non-dividing condition known as cell-cycle arrest, or senescence. It’s believed this occurs to prevent cells from going rogue and turning cancerous. Ideally, they should die by the process known as apoptosis, but as we age, more and more frequently they don’t. They become zombie cells – unable to kill themselves or resume normal function. Senescent cells secrete molecules that cause inflammation in an effort to attract immune cells that would usually clear them. But for reasons that are not fully known, as we age, persistently senescent cells accumulate, leading to a vast number of age-related diseases. Oisín is developing a highly precise, patent-pending, DNA-targeted intervention to clear these cells. As a recent study has shown, clearing senescent cells both reduces negative effects of aging pathologies and also extends median lifespan and survival.* Baker, Darren J., et al. "Naturally occurring p16Ink4a-positive cells shorten healthy lifespan." Nature 1038.16932 (2016) Emerging Company Showcase Targeting Metabesity October 13, 2022

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