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What is Kratom? A Pharmacologist's Perspective

Kratom use is widespread in the United States, as it is available as a herbal supplement. In this video, I will give pharmacologists perspective of what it is and what kind of effects it produces, while briefly discussing the pharmacology of mitragynine/7-hydroxymitragynine. I'd be happy to hear your thoughts on kratom and continue the discussion down below in the comments section. For more in-depth videos related to neuropharmacology, subscribe to my channel! IG: @neuropharmacist Twitter: @samuelkohtala www.neuropharmacist.com References: Chemical composition and biological effects of kratom (Mitragyna speciosa): In vitro studies with implications for efficacy and drug interactions D A Todd, J J Kellogg, E D Wallace, M Khin, L Flores-Bocanegra, R S Tanna, S McIntosh, H A Raja, T N Graf, S E Hemby, M F Paine, N H Oberlies, N B Cech PMID: 33154449 DOI: 10.1038/s41598-020-76119-w Signaling diversity of mu- and delta- opioid receptor ligands: Re-evaluating the benefits of β-arrestin/G protein signaling bias Graciela Pineyro, Karim Nagi PMID: 33383156 DOI: 10.1016/j.cellsig.2020.109906 Kratom Use and Toxicities in the United States William Eggleston , Robert Stoppacher, Kyle Suen, Jeanna M Marraffa, Lewis S Nelson PMID: 31099038 DOI: 10.1002/phar.2280 #kratom #whatiskratom