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Session 4: Apply a gender lens to research and innovation Sex and gender are important determinants of health and critical variables in scientific research, although too often disregarded. This oversight can significantly compromise study rigour and limit the relevance of research findings. Vaccine research and development should take into consideration sex and gender when developing and testing vaccine candidates for safety and efficacy, as well as when prioritizing products for development or roll-out. During the fourth webinar of this series experts from Italian National Institute for Health/Centre for Gender Specific Medicine and from WHO will explain how sex and gender have consequences in vaccine research, development and roll-out, and how they impact immune responses. We will also learn what tools are available to promote more transparent research and reporting practices, such as the Sex and Gender Equity in Research (SAGER) guidelines, recently adopted by WHO.