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QTL mapping

Detection of QTL is often limited by several factors such as genetic properties of QTL, environmental effects, population size and experimental error. Hence, it is desirable to independently confirm QTL mapping studies. Such confirmation studies may involve inde¬pendent populations constructed from the same parental genotypes or closely related geno¬types used in the primary QTL mapping study. Sometimes, larger population sizes may also be used. Furthermore, some recent studies have proposed that QTL positions and effects should be evaluated in independent populations because QTL mapping based on typical population sizes results in a low power of QTL detection and a large bias of QTL effects.