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Derek Lowe, PhD: A Medicinal Chemist’s Thoughts on Drug Discovery and the Future of Pharma

In this conversation, Daniel Belkin and Mitch Belkin interview Derek Lowe, PhD, about drug discovery, clinical trials, drug patents, Alzheimer’s disease, the FDA, and his blog “In The Pipeline”. They discuss the potential role for machine learning in pharmaceutical development, whether Big Pharma spends excessively on marketing, and much much more. 00:11: Introduction Derek Lowe 01:15: Overview of Drug Discovery 16:50: Machine Learning for Drug Discovery 19:05: Why are clinical trials so expensive? 21:46: FDA 26:11: Regulatory Nationalism 28:10: Drug Patents (small molecules vs biologics) 34:55: Improving the FDA 37:12: Does Pharma make too much money? 42:13: Overrated/Underrated 50:07: Blog: "In the pipeline" 56:26: Academic Journals 1:01:59: Rapidfire questions Who is Derek Lowe? Derek Lowe, PhD, is a medicinal chemist who works in preclinical drug discovery. He received a PhD in organic chemistry from Duke University and completed a Humboldt Fellowship in Germany for his post-doc. His blog about the pharmaceutical industry “In The Pipeline” has been continuously operating since 2002. For more info: Website: https://externalmedicinepodcast.com/d... Subscribe: https://bit.ly/3Qia4md Follow us on Twitter: https://bit.ly/3Vu3OKS Consider donating: https://bit.ly/3rWPyge