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The trailblazing chronobiologist Carrie Partch has a deep fascination with the biochemical mechanisms that living cells use to track time. Utilizing state-of-the-art nuclear magnetic resonance (NMR) technology and crystallography, her laboratory delves into the intricate workings of pivotal clock molecules such as CLOCK, BMAL1, and the PER and CRY proteins in our cells, investigating their roles in the regulation of circadian rhythms that control the human sleep-wake cycle. Despite the challenges of an ALS diagnosis, Partch is undeterred in her quest to unravel the mysteries of how the human body synchronizes itself with the natural cycles of planet Earth. Read the full article at Quanta Magazine: https://www.quantamagazine.org/in-our... 00:00 Biological clocks and chronobiology 01:21 The history of the study of biological clocks 02:30 Circadian rhythms govern more than just sleep-wake cycle 03:10 How modern life negatively impacts biological clock 03:50 Using Nuclear Magnetic Spectroscopy to study the proteins involved in the clock 05:30 How clock proteins regulate the 24-hour body clock 06:40 Fixing broken biological clocks VISIT our Website: https://www.quantamagazine.org LIKE us on Facebook: / quantanews FOLLOW us Twitter: / quantamagazine Quanta Magazine is an editorially independent publication supported by the Simons Foundation: https://www.simonsfoundation.org/ #biology #circadianrhythm #biologicalclock