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What causes weight loss, oral thrush & hairy leukoplakia with negative HIV tests?

Let me answer this in two levels. HIV is one of the infections we need to consider but if someone is having weight loss, that individual needs to be evaluated thoroughly because other infections has to be kept in mind. Weight loss can happen because of other disease, it can happen because thyroid disease, tuberculosis, could be because of cancers could be anything. So meet a physician who has expertise in managing this, as regards oral thrush and oral hairy leucoplakia is if a person is repeatedly HIV negative, some of the common causes for oral thrush besides the immune system becoming weak or the immunodeficiency because of the HIV are of they are on medications such as steroid inhalers or on other medications which change the bacteria in mouth which can result in thrush. One also has to consider sometimes the fact that these conditions may be misdiagnosed, sometimes just a normal coating of the tongue can be misdiagnosed as oral hairy leucoplakia and oral thrush and these things needs to be kept in mind and an experienced physician with expertise in this such as an experienced HIV doctor will be able to differentiate or make put the difference between true oral thrush and true oral hairy leucoplakia and something benign like coating. What actually happens is the mind and the body is not separate. In our practice we see everyday in people coming from various parts of the country and the world where someone has had the exposure and following the exposure there is a whole range of emotions such as fear, such as anxiety, shame, stigma. It is hard to discuss these things. Because the test comes as negative repeatedly, but these emotions are so traumatising, they look on the internet and find all kinds of information and some of them are not reliable and they are unable to process and accept the fact that they are actually negative and move on. In order to help in this situation, one needs to meet with an integrated team where there is a psychologist and an HIV expert or HIV doctor working closely together to create a programme for someone suffering from this and if done right and if there is good engagement by the patient, who is going through these symptoms, people feel excellent outcomes and people do feel much better. So I urge you to discuss these thigs with an HIV team where a psychologist and an HIV expert are working together.