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In this presentation by Dr. Robert Lustig at Emery Pharma, Dr. Lustig, a pediatric endocrinologist and expert on the metabolic impacts of sugar, discussed the profound effects of fructose and other environmental factors on obesity. He emphasized that a gram of fructose causes more weight gain and fat deposition than a gram of any other substance, including fat itself. Dr. Lustig presented two prevailing models of obesity: the energy balance model and the carbohydrate-insulin model. He argued that neither fully explains the obesity epidemic, especially given the increase in obesity among infants who do not diet or exercise. Dr. Lustig introduced the concept of obesogens. A group of chemicals that disrupt endocrine function and promote fat storage. He highlighted the significant impact of these chemicals, particularly on mitochondrial function, and how they contribute to obesity. He presented the "Redux model," suggesting that reactive oxygen species (ROS) generated by these obesogens and certain foods like fructose lead to increased fat storage and infact Fructose is natural obesogen. He stressed the importance of addressing fructose consumption, which can be controlled by eliminating high fructose content from processed foods. Dr. Lustig's presentation underscored the complexity of obesity, influenced by diet, environmental chemicals, and genetic factors, and called for a comprehensive approach to prevention, starting with reducing sugar intake. #ObesityEpidemic #ChildhoodObesity #MetabolicHealth #SugarReduction #FructoseImpact #HealthEducation #DietMatters #PublicHealth #EnvironmentalObesogens #EndocrineDisruptors #SugarAddiction #HealthyLiving #PreventativeHealth #metabolicdisorders #NutritionScience #MitochondrialFunction Be sure to check Emery’s other videos relating to health on this YouTube channel: • Robert Lustig Speaks Truth: Must Lis... PLEASE Don't forget to subscribe! IMPORTANT KEYWORDS IN THIS PRESENTATION: Fructose - Mentioned as causing more weight gain and fat deposition compared to other nutrients. Obesity - The central topic, discussed extensively in terms of causes, models, and prevention. Metabolic - Related to metabolic impacts, metabolic syndrome, and metabolic diseases. Sugar - Focused on its effects on health, particularly in processed foods. Diet - The role of diet in health and obesity, including dietary models and recommendations. Insulin - Discussed in the context of the carbohydrate-insulin model of obesity. Oxidative Stress - Related to reactive oxygen species (ROS) and their role in metabolism and obesity. Mitochondria - Highlighted as a crucial aspect of energy metabolism and a target of obesogens. Obesogens - Chemicals that contribute to obesity, discussed in terms of environmental exposure. Nutrition - Broad discussions on nutritional factors influencing health and disease, especially related to obesity and metabolism. About Emery Pharma: Emery Pharma is deeply committed to advancing public health and exclusively focuses on projects that enhance the well-being of both individuals and the environment. As a comprehensive contract research laboratory, Emery Pharma provides extensive support across the entire spectrum of pharmaceutical development, covering small molecule drugs, biologics, biosimilars, gene therapy, botanicals, and more. Emery Pharma's array of premium services includes analytical and bioanalytical solutions, microbiology and cell biology services, drug and impurity characterization, and comprehensive R&D with cGMP/GLP support. The Emery Pharma team excels in customizing innovative solutions tailored to the unique requirements of each client. They seamlessly oversee the entire process, from initial drug discovery to thorough data analysis and insights generation. Their expertise allows them to tackle scientific challenges proactively, ensuring clients avoid unnecessary setbacks. Emery Pharma's accomplished chemists and biologists harness state-of-the-art technology, encompassing cutting-edge tools such as high-resolution mass spectrometry (Orbitrap), triple quad LC-MS/MS, GC-MS, preparative HPLC, and 400 MHz multinuclear NMR. For further details, please don't hesitate to reach out to Emery Pharma at [email protected] or explore their website at: https://emerypharma.com/