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This episode is with Denis Noble. He is a renowned biologist, physiologist, and systems theorist, known for his pioneering research in the fields of cardiac physiology and systems biology. Noble's early work on the electrical activity of the heart was centered on this topic, and he was the first to put forth the notion of the cardiac action potential, which is now generally recognized in the field. He has also contributed significantly to our understanding of cardiac arrhythmias, irregular heart rhythms that can cause serious health concerns. In addition to his work in cardiac physiology, Noble has been a critical player in the development of systems biology, which aims to comprehend complex biological systems by integrating data from different sources. He has also been a vocal proponent of using mathematical and computational approaches in biology, and his work has contributed to developing a new paradigm for biological research. In this conversation we talk about the topics related to evolution, including Neo-Darwinism, the role of DNA as information, the use of genes as templates for evolution, the emerging field of epigenetics, the significance of bioelectricity, and potential future directions for evolutionary research. Guest info: Website: https://www.dpag.ox.ac.uk/team/denis-... Google scholar: https://scholar.google.com/citations?... Amazon: https://www.amazon.com/Books-Denis-No... Episode links: Website: https://www.reasonwithscience.com/hom... Youtube: • What drives evolution | Denis Noble |... Spotify: https://open.spotify.com/episode/5DtK... Apple podcast: https://podcastsconnect.apple.com/my-...|-denis-noble-|-reason-with-science-|-darwin-|-selfish-genes-|-richard-dawkins/714742fe-f764-44f6-ac50-bb4e52dabd1f Google podcast: https://podcasts.google.com/feed/aHR0... Follow Reason with Science: Website: https://www.reasonwithscience.com/ Youtube: https://www.youtube.com/channel/reaso... Spotify: https://open.spotify.com/show/5qFLGsP... Apple podcast: https://podcasts.apple.com/us/podcast... Google podcast: https://podcasts.google.com/feed/aHR0... Timestamps: 00:00:00 Introduction 00:00:58 DNA as the information in biological systems 00:20:30 What drives evolution? 01:00:49 Horizontal gene transfer 01:05:03 What is an organism? 01:23:08 Importance of metaphors 01:31:00 What is a gene? 01:31:57 Evolution of species 01:39:03 Artificial life 01:41:04 Thank you! More on Reason with Science: 1) Chemistry of life and death | Nick Lane | Reason with Science | Origin of life | Biochemistry ( • Chemistry of life and death | Nick La... ) 2) Collective intelligence of cells | Michael Levin | Reason with science | Bioelectricity | Biology ( • Collective intelligence of cells | Mi... ) 3) Powering the complexity of life with Michael Levin and Nick Lane | Reason with Science | Biology ( • Powering the complexity of life with ... ) 4) How multicellularity evolves | William Ratcliff | Reason with Science | Origin and evolution of life ( • How multicellularity evolves | Willia... ) 5) The evolutionary origins of a good society | Nicholas Christakis | Reason with Science | Psychology ( • The evolutionary origins of a good so... ) More talks/conversations of Denis: 1) Richard Dawkins and long-time rival Denis Noble go head to head on the selfish gene | Who is right? ( • Richard Dawkins and long-time rival D... ) @TheInstituteOfArtAndIdeas 2) Prof Denis Noble - Dance to the Tune of Life Lecture ( • Prof Denis Noble - Dance to the Tune ... ) @voicesfromoxfordUK 3) Can chemistry solve the origin of life? Perry Marshall, Denis Noble and Lee Cronin ( • Can chemistry solve the origin of lif... ) @PremierUnbelievable #reasonwithscience #evolution #biology