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Measurement Of Glomerular Filtration Rate In Conscious Mice l Protocol Preview

Watch the Full Video at https://www.jove.com/v/50330/a-high-t.... A High-throughput Method for Measurement of Glomerular Filtration Rate in Conscious Mice - a 2 minute Preview of the Experimental Protocol Timo Rieg University of California, San Diego , Division of Nephrology-Hypertension, Department of Medicine; San Diego VA Healthcare System,; Measurement of glomerular filtration rate (GFR) is the gold standard for kidney function assessment. Here we describe a high-throughput method which allows the determination of GFR in conscious mice by using a single bolus injection, determination of fluorescein isothiocyanate (FITC)-inulin in plasma and calculation of GFR by a two-phase exponential decay model. Visit https://www.jove.com?utm_source=youtube&utm_medium=social_global&utm_campaign=reseach-videos-2022 to explore our entire library of 14,000+ videos of laboratory methods and science concepts. JoVE is the world-leading producer and provider of science videos with the mission to improve scientific research and education. Millions of scientists, educators, and students at 1500+ institutions worldwide, including schools like Harvard, MIT and Stanford benefit from using JoVE's extensive library of 14,000+ videos in their research,education and teaching. Subscribe to our channel:    / jovejournalofvisualizedexperiments  

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