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All cellular protein building and much of the cellular gene expression occurs through the two principal steps called transcription and translation. In transcription, DNA’s information is encoded or “transcribed” into RNA. For genes that code for proteins, the RNA is called messenger or mRNA. The process begins when RNA polymerase opens the double helix of DNA, like the slider on a zipper. It unwinds the DNA double helix and pries the two DNA strands apart. As the RNA polymerase continues down the length of the DNA, several actions take place. It reads one strand of the DNA and transcribes the DNA’s information. It creates an mRNA version of the DNA or “transcript.” The mRNA transcript is a complimentary copy of the DNA sequence. When the transcription ends and the mRNA transcript is complete, it separates from the DNA template, and exits the nucleus through a nuclear pore. The transcript enters the cytoplasm on its way to the next step in the process of polypeptide synthesis: translation.