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Systemic Corticosteroids (Part III) in Dermatology - IV Pulse Therapy

Hi. With this video, we will discuss Intravenous Pulse Therapy with Systemic Corticosteroids (Part 3) in Dermatology, and be better prepared for treating our patients. This video is directed towards dermatologists and is not at all advisory for non-medical personnel. Introduction - 00:00 Agents - 06:30 The rationale of pulse therapy - 10:08 Mechanism of Action - 13:42 Administration - 18:15 Monitoring - 20:55 Side-effects - 24:10 Dexamethasone-Cyclophosphamide Pulse [DCP] - 26:00 Methylprednisolone-Cyclophosphamide Pulse [MCP] - 29:50 Dexamethasone-Azathioprine Pulse [DAP] - 30:43 Dexamethasone-Methotrexate Pulse [DMP] - 32:06 Prednisolone Pulse Therapy [PPT] - 33:46 Topical Steroid Pulse Therapy [TSP] - 34:29 Oral Mini Pulse [OMP] - 36:42 Oral Betamethasone Pulse [OBP] - 40:13 Combination with other modalities - 42:35 Further Reading - 48:48 Please Watch Part 1 and Part 2 - 49:26 Articles for further reading: 1. Gupta G, Jain A, Narayanasetty NK. Steroid pulse therapies in dermatology. Muller J Med Sci Res 2014;5:155-8 2. Sinha A, Bagga A. Pulse steroid therapy. Indian J Pediatr. 2008;75(10):1057-1066. doi:10.1007/s12098-008-0210-7 3. Mustafi S, Sinha R, Hore S, Sen S, Maity S, Ghosh P. Pulse therapy: Opening new vistas in treatment of pemphigus. J Family Med Prim Care 2019;8:793-8. 4. Ramam M. Dexamethasone pulse therapy in dermatology. Indian J Dermatol Venereol Leprol 2003;69:319-322 5. Pasricha JS. Pulse therapy as a cure for autoimmune diseases. Indian J Dermatol Venereol Leprol. 2003;69(5):323-328. 6. Edel Y, Avni T, Shepshelovich D, et al. The safety of pulse corticosteroid therapy- Systematic review and meta-analysis. Semin Arthritis Rheum. 2020;50(3):534-545. doi:10.1016/j.semarthrit.2019.11.006