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Understanding chemotherapy-related nerve pain | Dr Marta Seretny

In this short talk, Dr Marta Seretny presents the preliminary results of a study seeking to identify which cancer chemotherapy patients will go on to develop the side-effect of peripheral nerve pain. Around 2 in 3 chemotherapy patients develop peripheral nerve pain, or neuropathy. 3 in 10 patients who survive their cancer continue to suffer from this chemotherapy-induced peripheral neuropathy, or CIPN, after the treatment has ended. 70,000+ new cases of CIPN are diagnosed every year. CIPN can cause patients to require a lower treatment dose during chemotherapy, or even force them to stop treatment altogether. Dr Seretny's work is the first study looking at the brain's influence on CIPN, despite the brain being central to perception of pain in the outer body. She used fMRI imaging to look at the brains of 30 patients before, during and after chemotherapy. By identifying areas of activity in the brain that correlate with increased risk of developing CIPN, Dr Seretny hopes to use these biomarkers to contribute to the development of personalised chemotherapy. Dr Marta Seretny is an anaesthetic registrar in the South East Scotland School of Anaesthesia, Edinburgh, and a Wellcome Trust Clinical Academic PhD Fellow with the Scottish Translational Medicine and Therapeutics Initiative. Dr Seretny's research can be viewed in full here: http://anesthesiology.pubs.asahq.org/... http://www.sciencedirect.com/science/... This lecture was given as part of the Academy of Medical Sciences Spring Meeting, 2016. To read more about the Spring Meeting, visit https://acmedsci.ac.uk/grants-and-sch... We are the independent body in the UK representing the diversity of medical science. Our mission is to advance biomedical and health research and its translation into benefits for society. Find the Academy of Medical Sciences online: Website: http://acmedsci.ac.uk/ Twitter:   / acmedsci   Facebook:   / acmedsci   Instagram:   / acmedsci