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168. Digestion & Absorption Of Proteins

𝐒𝐮𝐛𝐬𝐜𝐫𝐢𝐛𝐞 𝗙𝐨𝐫 𝗠𝐨𝐫𝐞 𝗜𝐧𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐨𝐧 𝐨𝐧 𝗛𝐞𝐚𝐥𝐭𝐡 👩‍⚕‍ 𝐚𝐧𝐝 𝗠𝐞𝐝𝐢𝐜𝐢𝐧𝐞💉🩺💊 𝐘𝐨𝐮𝐭𝐮𝐛𝐞 :    / @draishwaryakelkar   📌𝗙𝗮𝗰𝗲𝗯𝗼𝗼𝗸 :   / draishwaryakelkar   📌𝗧𝘄𝗶𝘁𝘁𝗲𝗿:   / aishwayadr   📌𝗜𝗻𝘀𝘁𝗮𝗴𝗿𝗮𝗺 :   / clinical.learning   Amino acids are absorbed by a co-transport mechanism with sodium ions. Both sodium ion and amino acid combine with a cell surface protein receptor. There are different receptors for the groups: -neutral amino acids -basic amino acids -acidic amino acids -imino acids In addition, certain amino acids may have there own specific transporter e.g. proline. The receptor then conveys both molecules to the inside of the cell. The energy for this transport is derived from the concentration gradient for sodium across the cell membrane. Na-K ATPase transporters actively and continuously pump sodium ions outwards to maintain the gradient. After absorption into an enterocyte, amino acids can have one of two fates: -a minority, particularly glutamate, are oxidized to liberate energy -the majority are passed to the portal circulation The movement of sodium into the cell is accompanied by chloride and water movement into the intercellular space and eventually the bloodstream. There may be a small amount of absorption of amino acids as di- and tripeptides. These are probably digested within the cell to amino acids. Defects of the amino acid protein carrier can lead to conditions like Hartnup's disease and cystinuria. #acids #aminoacids #mbbs #biochemistry #absorptionofproteins #digestionandabsorptionofproteins #chemistry #medicalstudents #medico