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Dr. Brendon Neuen is a Nephrologist and Director of the Kidney Trials Unit at Royal North Shore Hospital, and Senior Research Fellow at The George Institute for Global Health in Sydney, Australia. He graduated with 1st Class Honors and the Academic Medal from James Cook University, holds Masters in Global Health from the University of Oxford, PhD from the University of New South Wales. He is a Fellow of the Royal Australasian College of Physicians and the American Society of Nephrology. He is widely recognized for his expertise in cardio-renal-metabolic medicine. Dr Neuen established the SGLT2 Meta-Analysis Cardio-Renal Trialists' Consortium, bringing together data on more than 90,000 patients to better understand the effects of this class of medicines in different types of patients. His work has directly informed more than 25 major international and national guidelines, position papers and scientific statements which optimal care for people with type 2 diabetes and kidney disease. Learning Objectives: 1. Recall the evidence base for newer therapies that reduce cardiorenal risk in people with type 2 diabetes and CKD 2. Understand the potential efficacy and safety considerations with combination therapy with guideline recommended therapies for diabetes and CKD 3. Recognize overlap and distinctions between different guideline recommendations for people with CKD