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How to find the cause of jaundice quickly and with the most basic tests? In this video, I will present my step-by-step approach to jaundice, how to narrow down the possibilities, and diagnose different types of liver disease, biliary obstruction, hemolytic anemia, and other possible causes of jaundice. Lecture summary in PDF: https://drviktorkotarski.podia.com/le... If you want to learn how to recognize life-threatening infections like sepsis and CNS infections as early as possible, I highly recommend you take my free online course! A Clinical Approach to Serious Infections in Adults: What Every Physician Should Know: https://drviktorkotarski.podia.com/re... DISCLAIMER: Please, always keep in mind that my videos are intended for educational purposes only. The content of my videos is NOT medical advice. I do not practice medicine over the Internet. If you are a patient and have any questions about your health, please talk to your doctor. CHAPTERS: 00:00 Is it really jaundice? 01:01 The metabolism of bilirubin 02:25 Viral hepatitis 03:42 Jaundice, fever, and sepsis 06:01 Medications, alcoholic hepatitis, and cirrhosis 07:35 Biliary obstruction 08:11 Hemolysis and hemolytic anemia 10:54 Unconjugated hyperbilirubinemia and Gilbert's syndrome 12:04 Conjugated hyperbilirubinemia 12:19 Liver function tests (ALT, ALT, ALP, GGT, albumin, INR) 14:23 CBC with differential and a peripheral blood smear 16:09 Abdominal ultrasound and CT scan REFERENCES & RECOMMENDED READING: 1. Beckingham IJ, Ryder SD. ABC of diseases of liver, pancreas, and biliary system. Investigation of liver and biliary disease. BMJ. 2001 Jan 6;322(7277):33–6. 2. Gondal B, Aronsohn A. A Systematic Approach to Patients with Jaundice. Semin Intervent Radiol. 2016 Dec;33(4):253–8. 3. Ruiz ARG, Crespo J, Martínez RML, Iruzubieta P, Mercadal GC, Garcés ML, et al. Measurement and clinical usefulness of bilirubin in liver disease. Advances in Laboratory Medicine / Avances en Medicina de Laboratorio. 2021 Sep 1;2(3):352–61.