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Why Do People With Certain Genetic Makeup Need More Choline In Their Diets?

Choline was declared an essential nutrient by the Institute of Medicine in 1998. Choline is required for several important functions in the body, including the regulation of the muscular system, nervous system, and liver function. It also helps maintain an active metabolism. Choline is also needed to produce acetylcholine, which is a neurotransmitter. Neurotransmitters help transmit signals from the brain to the target cells. Along with vitamin B9 and B12, choline is involved in the synthesis of DNA. Small amounts of choline are produced in the liver, but this is not enough to meet daily requirements. This essential nutrient needs to be supplemented through diet. The requirements vary from person to person based on their age, genetic makeup, and various other factors. Choline deficiency can increase the risk of developing certain health conditions like non-alcoholic Fatty Liver disease, obesity, hypertension, and liver damage. Certain genes also influence your choline requirements. The PEMT gene is one such example. This gene contains instructions for making an enzyme that is involved in the production of choline. Variants in this gene affect the levels of choline in the body. In case you are at risk for choline deficiency, talk to your doctor. You might need to take choline supplements apart from eating a diet rich in choline. Learn More: https://www.xcode.life/genes-and-nutr... Segments: Introduction (00:00) Importance of Choline (00:24) Choline Requirements (01:19) Choline Deficiency (01:46) Choline-rich Foods (02:31) How Do Genes Influence Choline Absorption From Diet? (02:59) Analyzing your Genetic Risk for Choline Deficiency (03:26)