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Acute Myeloid Leukemia (AML) & Chronic Myeloid Leukemia (CML) (Pathophysiology) | Sketchy Medical

Try the 7-day free trial to watch this lesson and more from our Pathophysiology https://www.sketchy.com/explore/medic... We’re at the Museum of Myeloid Art, where we’ll break down the key differences between AML (Acute Myeloid Leukemia) and CML (Chronic Myeloid Leukemia). AML is aggressive and rapidly progressive, often a medical emergency, while CML has a more chronic and slower course. We explore how AML is characterized by a high number of immature myeloblasts, whereas CML involves more mature granulocyte forms. Both leukemias typically present in patients around 60 years old, with distinct genetic markers: AML with the PML-RARA translocation and CML with the BCR-ABL fusion protein. We also discuss the diagnostic criteria for AML, including the presence of 20% blasts in the bone marrow, and the unique progression of CML, which can accelerate into a blast phase resembling AML. — Sketchy is the #1 visual learning platform brought to you from the creators of SketchyMicro and SketchyPharm. We turn what you need to know for your course prep and exams and into engaging, artful stories that you’ll remember forever. Rooted in an ancient memorization technique called the ‘method of loci,’ The Sketchy Method is proven to accelerate learning, increase retention, and improve test scores. (Trust us, we’re doctors.) Our comprehensive one-of-a-kind curriculum covers everything you need to know to conquer any subject—and have fun while doing it. Sketchy has programs to help your study and improve your scores for USMLE, MCAT, PANCE, NCLEX, & NAPLEX! Follow us:   / sketchylearning     / sketchymcat     / sketchylearning     / discord     / sketchylearning     / sketchylearning   --- Medical disclaimer: Sketchy Group LLC does not provide medical advice. Sketchy Group LLC and the content available on Sketchy Group’s properties (Sketchy.com, YouTube, and other channels) do not provide a diagnosis or other recommendation for treatment and are not a substitute for the professional judgment of a healthcare professional in diagnosis and treatment of any person or animal. The determination of the need for medical services and the types of healthcare to be provided to a patient are decisions that should be made only by a physician or other licensed health care provider. Always seek the advice of a physician or other qualified healthcare provider with any questions you have regarding a medical condition.