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SPEAKER- Prof Helen Coleman- “Insights from Molecular Pathology Epidemiology studies of Gastrointestinal Neoplasia” Professor of Cancer Epidemiology, Centre for Public Health, Queen's University Belfast. Professor Coleman leads Cancer Epidemiology Research Group at the Centre for Public Health at Queen's University Belfast; she is also Deputy Director of the Northern Ireland Cancer Registry. This talk will outline the application of molecular pathology epidemiology (MPE) studies to gastrointestinal neoplasia progression. MPE studies investigate the interaction between biomarkers and epidemiological risk factors to better understand why some patients with pre-malignant conditions of the gastrointestinal tract develop cancer, and how these may interact to influence survival following a cancer diagnosis. Professor Coleman will outline her current research from Cancer Research UK and other funded MPE studies of oesophageal and colorectal neoplasia progression. This includes findings from a large inter-disciplinary cohort of 700 population-representative Stage II and III colon adenocarcinoma patients diagnosed between 2004-2008 in Northern Ireland, and new research within the UK OCCAMS consortium of over 3,000 oesophageal cancer patients.