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Primary progressive aphasia as a model to understand the neurobiology of language

CIC Imaging Lecture Series lecture by Maxime Montembeault, Assistant Professor, Department of Psychaitry, McGill University; Researcher, Douglas Research Centre. This talk will systematically explore the different variants of primary progressive aphasia (PPA), shedding light on their distinct clinical characteristics and manifestations. An emphasis will be placed on elucidating how the specific patterns of brain damage associated with each PPA variant serve as crucial insights into the intricate neural mechanisms governing speech and language functions. Specific aspects such as semantic memory, grammar, motor speech, naming, and sentence repetition will be dissected, offering a comprehensive understanding of how PPA provides a unique lens through which we can unravel the mysteries of language processing in the brain. *Patient videos exemplifying various speech/ language symptoms have been removed from this public edit.