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Deep Learning for Protein Folding - Lecture 17 - MIT Deep Learning in Life Sciences (Spring 2021)

MIT 6.874/6.802/20.390/20.490/HST.506 Spring 2021 Prof. Manolis Kellis Guest lecturers: Bruno Correia, Jinbo Xu, Mohammed AlQuraishi Deep Learning in the Life Sciences / Computational Systems Biology Playlist:    • MIT Deep Learning in Life Sciences - ...   Latest slides and course today: http://compbio.mit.edu/6874 Spring 2021 slides and materials: http://mit6874.github.io/ 0:00 Introduction 8:12 Protein surfaces 9:45 Geometric deep learning 13:08 Molecular surface interaction fingerprints 24:42 De novo design of protein-protein interactions 29:30 Protein structure prediction 39:22 Coevolution analysis 43:28 Previous supervised learning methods 49:21 Deep learning 56:54 Building a 3d structure from pairwise distance 1:01:00 Ideas for improvement 1:11:59 Algorithm space for protein structure prediction 1:19:45 Decomposing algorithm space 1:28:37 RGN 1:35:02 RGN2 1:38:53 Model performance