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Physiologic estrogen: my preferred approach to HRT for healthy longevity | Felice Gersh, MD

In this talk, I discuss both the typical low dose static approach to HRT and my preferred approach, physiologic cyclic. I explain the benefits, short-comings, and downsides of the low dose static approach and the benefits and drawbacks of physiologic cyclic. Also, there IS data that dose matters and that cyclic is safe. Many of the cornerstone hormone studies, including the ELITE and KEEP studies, were done with cyclic hormones. It was the WHI that used low dose cyclic so how that became the go-to, well, it's because it's the easiest approach, not the best. In this talk, I cover: What physiologic means Why we want enough estrogen to create growth factors Why growth factors will grow the uterine lining And how we can use that as a sign that growth factors are working throughout the body And finally, why physiologic estrogen requires cyclic progesterone that induces a monthly period-like bleed. "If you grow it, you must shed it." Watch for my latest Instagram lives at   / dr.felicegersh   I am a full time practicing doctor. I see patients in my office in Irvine, CA and worldwide via telemedicine. If you need more healthcare assistance than I can provide in a video series, please contact my office: https://integrativemgi.com/​​ ---- Contents of this video -------------------------- 00:00 - What is physiologic estrogen? 03:11 - Basic benefits of low dose static HRT 07:09 - No monthly bleed 08:30 - Healthy longevity 10:21 - Benefits of physiologic dosing 12:45 - Replicating the menstrual cycle 14:46 - My approach to physiologic dosing 16:07 - Dose matters 17:16 - The uterus isn't a target of HRT; it's a bystander 20:40 - Grow factors and cellular rejuvenation 22:15 - The role of progesterone 24:50 - Low dose static is unnatural 27:46 - Physiologic recreates the body's natural hormonal state 30:07 - Studies that support cyclic