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The Michael Addition + 1,4 Additions with Soft Nucleophiles 3 года назад


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The Michael Addition + 1,4 Additions with Soft Nucleophiles

https://joechem.io/videos/43 for video on jOeCHEM and attached worksheet + solution (below video on jOeCHEM aka the link) In this video, we look at a functional group called enones--or alpha, beta unsaturated carbonyls--and how they are prime candidates to be attacked by nucleophiles in a 1,4 fashion. We will specifically look at the Michael Addition, which is when an enolate (a soft nucleophile) attacks an enone. However, you can attack enones in a 1,4 fashion with any "soft" nucleophile, and we'll see an example of that by attacking an enone with a cuprate. Previous version of this video:    • Michael Additions + 1,4-Additions wit...   ======================================== Follow jOeCHEM on social media: If you're having an organic blast, please SUBSCRIBE: https://www.youtube.com/c/joechem?sub... LIKE and FOLLOW across social media: Facebook -   / joechemio   Instagram -   / joechem_io  

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