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What do opioids actually do in the brain? In this enlightening interview, ER doctor / double board certified child and adolescent psychiatrist, Dr. Dom Sportelli, and MedCircle host, Kyle Kittleson, break down the neuroscience 101 education you need on opiate use disorder, and other opioid addiction basics. Want access to 900+ videos like this one, live workshops, and more? Check out our Membership options at https://www.medcircle.com Discussion time codes: 00:00 Intro 00:42 Brain basics you need to know (serotonin vs dopamine vs endorphins) 02:05 The opiates that already exist in our brain (endorphins) 02:52 How the poppy plant imitates endorphins 03:40 Why opioids from a poppy plant are actually bad (How they impact the brain) 05:48 What happens when your brain gets "too much" of something? (IE opioids) 06:00 "Receptor down-regulation" and how it leads to drug tolerance 07:15 How it leads to withdrawal 08:49 The neuroscience of why quitting is so hard (how opioids change pain) 10:30 Key takeaways 12:04 how to watch more (detox, withdrawal, overdose management & more) #OpioidCrisis #Addiction #MentalHealth #mentalhealthawareness #mentalhealthmatters #opiates #opiate #opiods